N-Acetyl Epitalon Amidate (5 mg)

$110.00

SKU: YPB.232 Categories: ,

Description

A single-component research material supplied for controlled research environments. N-Acetyl Epitalon Amidate (5 mg) is a synthetic tetrapeptide analog designed for research exploring telomeric activity, aging-related signaling pathways, and pineal peptide biochemistry in model systems.Not for human use.


Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.


Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.


Quality & Manufacturing

All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.

Additional information

Weight 0.0625 lbs

Certificate of Analysis

Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.

View Certificate of Analysis
Testing Protocol
Third-Party Lab Verified Quantitative Assay Heavy Metals Screened
Sterility Testing (TAMC) Yeast & Mold Testing (TYMC)

Testing performed per USP compendial standards by independent analytical laboratory

Storage Instructions

All products from Apex Health Performance are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.

Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating regulatory peptides

6 Studies Found
100% Peer-Reviewed
PubMed Verified Source
In Vitro Study PubMed

CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.

Clinical science (London, England : 1979) 2025

The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.

View Full Study on PubMed
Structural Analysis PubMed

Adverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.

Diabetes, obesity & metabolism 2025

AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.

View Full Study on PubMed
Molecular Analysis PubMed

Neuropeptide signalling orchestrates T cell differentiation.

Nature 2024

Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.

View Full Study on PubMed
Mechanism Study PubMed

Comparative study of neuropeptide signaling systems in Hemiptera.

Insect science 2023

Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.

View Full Study on PubMed
Literature Review PubMed

Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics.

Pharmacological reviews 2022

The evolutionary origins of at least 30 neuropeptide signaling systems have been traced to the common ancestor of protostomes and deuterostomes. Groundbreaking advances in medicine and basic science influence how signaling peptides are defined today.

View Full Study on PubMed
Literature Review PubMed

Human proline specific peptidases: A comprehensive analysis.

Biochimica et biophysica acta. General subjects 2020

Two functions rely on the catalytic activity of the enzyme: one involved in a regulatory pathway associated with the ability of many PSPs to hydrolyze peptide hormones and neuropeptides, and the other involved in the trophic pathway associated with the proteolysis of total cellular protein or Pro-containing dietary proteins in the digestive tract. A comparative analysis of PSPs can guide research to develop inhibitors that counteract the abnormalities associated with changes in PSP activity, and identify natural substrates of PSPs that will enable better understanding of the mechanisms of the action of PSPs in biological processes and disease.

View Full Study on PubMed
Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating regulatory peptides

In Vitro Study PubMed

CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.

Clinical science (London, England : 1979) 2025

The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.

View Full Study on PubMed
Laboratory Research PubMed

Adverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.

Diabetes, obesity & metabolism 2025

AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.

View Full Study on PubMed
Molecular Analysis PubMed

Neuropeptide signalling orchestrates T cell differentiation.

Nature 2024

Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.

View Full Study on PubMed
Mechanism Study PubMed

Comparative study of neuropeptide signaling systems in Hemiptera.

Insect science 2023

Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.

View Full Study on PubMed
Literature Review PubMed

Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics.

Pharmacological reviews 2022

The evolutionary origins of at least 30 neuropeptide signaling systems have been traced to the common ancestor of protostomes and deuterostomes. Groundbreaking advances in medicine and basic science influence how signaling peptides are defined today.

View Full Study on PubMed
Literature Review PubMed

Human proline specific peptidases: A comprehensive analysis.

Biochimica et biophysica acta. General subjects 2020

Two functions rely on the catalytic activity of the enzyme: one involved in a regulatory pathway associated with the ability of many PSPs to hydrolyze peptide hormones and neuropeptides, and the other involved in the trophic pathway associated with the proteolysis of total cellular protein or Pro-containing dietary proteins in the digestive tract. A comparative analysis of PSPs can guide research to develop inhibitors that counteract the abnormalities associated with changes in PSP activity, and identify natural substrates of PSPs that will enable better understanding of the mechanisms of the action of PSPs in biological processes and disease.

View Full Study on PubMed
TEST — CODE SNIPPETS IS WORKING
Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating regulatory peptides

In Vitro Study PubMed

CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.

Clinical science (London, England : 1979) 2025

The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.

View Full Study on PubMed →
Structural Analysis PubMed

Adverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.

Diabetes, obesity & metabolism 2025

AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.

View Full Study on PubMed →
Molecular Analysis PubMed

Neuropeptide signalling orchestrates T cell differentiation.

Nature 2024

Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.

View Full Study on PubMed →
Mechanism Study PubMed

Comparative study of neuropeptide signaling systems in Hemiptera.

Insect science 2023

Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.

View Full Study on PubMed →
Literature Review PubMed

Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics.

Pharmacological reviews 2022

The evolutionary origins of at least 30 neuropeptide signaling systems have been traced to the common ancestor of protostomes and deuterostomes. Groundbreaking advances in medicine and basic science influence how signaling peptides are defined today.

View Full Study on PubMed →
Literature Review PubMed

Human proline specific peptidases: A comprehensive analysis.

Biochimica et biophysica acta. General subjects 2020

Two functions rely on the catalytic activity of the enzyme: one involved in a regulatory pathway associated with the ability of many PSPs to hydrolyze peptide hormones and neuropeptides, and the other involved in the trophic pathway associated with the proteolysis of total cellular protein or Pro-containing dietary proteins in the digestive tract. A comparative analysis of PSPs can guide research to develop inhibitors that counteract the abnormalities associated with changes in PSP activity, and identify natural substrates of PSPs that will enable better understanding of the mechanisms of the action of PSPs in biological processes and disease.

View Full Study on PubMed →

Important Research Notice: These products are research chemicals intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any therapeutic purpose. Sold strictly for scientific research applications only.

Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥98%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥98% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

All products are supplied in lyophilized powder form within sterile, sealed vials. This format provides:

  • Maximum stability: Extended shelf life compared to liquid solutions
  • Precise measurement: Researchers can work with desired quantities
  • Contamination protection: Sealed vials prevent environmental exposure
  • Shipping durability: Powder form is more stable during transit

Lyophilized peptides:

  • Store at -4°F for long-term storage (up to 24 months)
  • Store at 36-46°F (refrigerated) for short-term storage (up to 3 months)
  • Keep away from light, moisture, and repeated temperature fluctuations

We supply research-grade peptides to:

  • Academic and university research laboratories
  • Pharmaceutical and biotechnology companies
  • Independent research institutions
  • Licensed professionals conducting legitimate scientific research

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥98% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

"Research Use Only" (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

We stand behind every product:

  • Quality guarantee: Full replacement or refund if products don't meet stated specifications
  • Shipping issues: Free replacement for damaged or lost shipments
  • Unopened returns: Accepted within 30 days for store credit
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⚠️ Research Use Only — Legal Acknowledgment

All products on this website are sold strictly for in vitro research and laboratory use only.

  • Not for human or veterinary use, consumption, or application
  • Not FDA-approved to diagnose, treat, cure, or prevent any disease
  • Buyer assumes full responsibility for legal compliance in their jurisdiction

By clicking "Accept," you confirm:

  • You are at least 21 years of age
  • You are a qualified researcher or laboratory professional
  • You represent the affiliation type selected above
  • You understand these products are for research purposes only