N-Acetyl Epitalon Amidate (5 mg)
$110.00
Certificate information is temporarily unavailable.
Description
A single-component research material supplied for controlled research environments. N-Acetyl Epitalon Amidate (5 mg) is a synthetic tetrapeptide analog designed for research exploring telomeric activity, aging-related signaling pathways, and pineal peptide biochemistry in model systems.Not for human use.
Documentation & Quality Assurance
Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.
Important Notice
This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.
Quality & Manufacturing
All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.
We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.
All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.
Additional information
| Weight | 0.0625 lbs |
|---|
Certificate of Analysis
Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.
View Certificate of AnalysisStorage Instructions
All products from Apex Health Performance are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.
Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.
Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.
Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.
⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.
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Research Use Only
The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.
Published Scientific Research
Peer-reviewed laboratory studies investigating regulatory peptides
Angiotensin-(1-9) attenuates diabetic cardiomyopathy by improving insulin resistance.
EXPERIMENTAL APPROACH: To investigate the role of angiotensin-(1-9), we first induced lipotoxic stress in the heart by high-fat diet (HFD) feeding in mice. Mechanistically, angiotensin-(1-9) does not affect insulin signalling in cardiomyocytes at baseline, whereas it significantly improves insulin action under lipotoxic stress through AT receptors and protein kinase A.
View Full Study on PubMedCGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.
The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.
View Full Study on PubMedAdverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.
AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.
View Full Study on PubMedNeuropeptide signalling orchestrates T cell differentiation.
Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.
View Full Study on PubMedDevelopment of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release.
In vivo studies with fibre photometry enabled direct recording of NOPLight binding to exogenous N/OFQ receptor ligands, as well as detection of endogenous N/OFQ release within the paranigral ventral tegmental area (pnVTA) during natural behaviors and chemogenetic activation of PNOC neurons.
View Full Study on PubMedComparative study of neuropeptide signaling systems in Hemiptera.
Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.
View Full Study on PubMedResearch Use Only
The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.
Published Scientific Research
Peer-reviewed laboratory studies investigating regulatory peptides
Angiotensin-(1-9) attenuates diabetic cardiomyopathy by improving insulin resistance.
EXPERIMENTAL APPROACH: To investigate the role of angiotensin-(1-9), we first induced lipotoxic stress in the heart by high-fat diet (HFD) feeding in mice. Mechanistically, angiotensin-(1-9) does not affect insulin signalling in cardiomyocytes at baseline, whereas it significantly improves insulin action under lipotoxic stress through AT receptors and protein kinase A.
View Full Study on PubMedCGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.
The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.
View Full Study on PubMedAdverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.
AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.
View Full Study on PubMedNeuropeptide signalling orchestrates T cell differentiation.
Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.
View Full Study on PubMedDevelopment of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release.
In vivo studies with fibre photometry enabled direct recording of NOPLight binding to exogenous N/OFQ receptor ligands, as well as detection of endogenous N/OFQ release within the paranigral ventral tegmental area (pnVTA) during natural behaviors and chemogenetic activation of PNOC neurons.
View Full Study on PubMedComparative study of neuropeptide signaling systems in Hemiptera.
Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.
View Full Study on PubMedResearch Use Only
The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.
Published Scientific Research
Peer-reviewed laboratory studies investigating regulatory peptides
Angiotensin-(1-9) attenuates diabetic cardiomyopathy by improving insulin resistance.
EXPERIMENTAL APPROACH: To investigate the role of angiotensin-(1-9), we first induced lipotoxic stress in the heart by high-fat diet (HFD) feeding in mice. Mechanistically, angiotensin-(1-9) does not affect insulin signalling in cardiomyocytes at baseline, whereas it significantly improves insulin action under lipotoxic stress through AT receptors and protein kinase A.
View Full Study on PubMed →CGRP alleviates lipopolysaccharide-induced ARDS inflammation via the HIF-1α signaling pathway.
The outbreak of immune inflammation in the lung is an important pathogenic mechanism of ARDS. CGRP can regulate the polarization of macrophages by targeting its receptor (receptor activity-modifying protein 1); reduce the proportion of M1 macrophages; increase the proportion of M2 macrophages; and reduce pathological injury, inflammation, oxidative stress, and apoptosis in lung tissue in LPS-induced ARDS both in vitro and in vivo.
View Full Study on PubMed →Adverse drug reaction patterns of GLP-1 receptor agonists approved for obesity treatment: Disproportionality analysis from global pharmacovigilance database.
AIMS: This study aims to compare adverse drug reaction patterns of liraglutide, semaglutide and tirzepatide-glucagon-like peptide-1 receptor agonists (GLP-1 RAs) approved for anti-obesity medications-to evaluate their real-world safety. The study focused on reports of adverse events associated with liraglutide, semaglutide and tirzepatide, selected based on warnings in the US Food and Drug Administration approval labels for each drug.
View Full Study on PubMed →Neuropeptide signalling orchestrates T cell differentiation.
Here we dissected the dynamic regulation of T1 cell differentiation during in vitro polarization, and during in vivo differentiation after acute viral infection. We found that RAMP3, a component of the receptor for the neuropeptide CGRP (calcitonin gene-related peptide), has a cell-intrinsic role in T1 cell fate determination.
View Full Study on PubMed →Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release.
In vivo studies with fibre photometry enabled direct recording of NOPLight binding to exogenous N/OFQ receptor ligands, as well as detection of endogenous N/OFQ release within the paranigral ventral tegmental area (pnVTA) during natural behaviors and chemogenetic activation of PNOC neurons.
View Full Study on PubMed →Comparative study of neuropeptide signaling systems in Hemiptera.
Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form an ancient signaling system, there is still a great deal of variety in neuropeptides and their receptors among different species within the same order.
View Full Study on PubMed →Important Research Notice: These products are research chemicals intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any therapeutic purpose. Sold strictly for scientific research applications only.