B12 (10ml)

$90.00

SKU: YPB.251 Category:

Description

A single-component research material supplied for controlled research environments. This 10 mL B12 research solution is designed for laboratory studies exploring cobalamin behavior, stability, and assay development in model systems.Not for human use.


Documentation & Quality Assurance

Each lot is sourced through our verified global supply chain with emphasis on traceability and quality control.These documents are reviewed internally and displayed as they become available. Independent third-party testing is also performed on select lots to confirm identity, purity, and alignment with our internal specifications.


Important Notice

This product is intended for laboratory research use only. It is not intended for human or veterinary use, and must not be used for diagnostic, therapeutic, or clinical purposes.
This material is not a drug, medical device, or dietary supplement, and has not been evaluated by the U.S. Food and Drug Administration.


Quality & Manufacturing

All materials are sourced from carefully vetted domestic and international manufacturing partners who follow quality systems consistent with ISO and cGMP principles. Each supplier is reviewed for reliability, documentation integrity, and transparency in testing.

We require a verified purity of 99% or higher and perform independent third-party spot testing to confirm that select lots meet our internal standards for identity, purity, and composition. Where available, endotoxin testing results are included on Certificates of Analysis to verify laboratory purity; their inclusion is for research quality assessment only and does not imply suitability for human or veterinary use.

All research materials are sealed for integrity and packaged for stability during storage and transport from manufacturing through final delivery.

Additional information

Weight 0.0625 lbs
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Published Scientific Research

Explore the full library of peer-reviewed studies, clinical data, mechanism breakdowns, and molecular specifications for B12 (10ml).

All research is sourced from PubMed-indexed journals for informational and educational purposes only. For Research Use Only (RUO). Not for human use.

View Full Research Library →

Certificate of Analysis

Every batch undergoes independent third-party laboratory analysis to verify identity, potency, and safety. Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis.

View Certificate of Analysis
Testing Protocol
Third-Party Lab Verified Quantitative Assay Heavy Metals Screened
Sterility Testing (TAMC) Yeast & Mold Testing (TYMC)

Testing performed per USP compendial standards by independent analytical laboratory

Storage Instructions

All products from Apex Health Performance are manufactured using a lyophilization (freeze-drying) process. This method is designed to maintain product integrity and allows vials to remain stable during shipping for approximately 3–4 months.

Once a vial is reconstituted with bacteriostatic water, it should be stored in the refrigerator to help maintain stability. Under these conditions, reconstituted material is generally considered stable for up to 30 days.

Lyophilization is a dehydration technique in which compounds are frozen and then exposed to low pressure. This causes the water in the vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure. This powder can be kept at room temperature until reconstitution.

Upon receipt, products should be stored away from heat and light. For short-term use, refrigeration at approximately 4°C (39°F) is suitable. For long-term storage (several months to years), vials may be placed in a freezer at approximately -80°C (-112°F). Freezing is the preferred method for preserving product stability over extended periods.

⚠️ Important Notice:
These products are intended for research use only. Not for human consumption.

Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

Research Database Updating

Scientific studies for this compound are being indexed. Please check back shortly.

Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating research peptides

Molecular Analysis PubMed

Description of TEMPI syndrome in Waldenström's macroglobulinemia.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 2025

BACKGROUND: TEMPI syndrome (telangiectasia, erythrocytosis with increased erythropoietin, monoclonal gammopathy, perinephritic fluid collections, and intrapulmonary shunts) was described by David Sykes in 2011. By the end of March 2025, we have found descriptions of 35 cases of TEMPI syndrome in the literature. Non-IgM monoclonal gammopathy of clinical significance was diagnosed in 23 patients, multiple myeloma in 10 patients and Waldenström's macroglobulinemia in only 2 cases. Sykes estimated

View Full Study on PubMed
Systematic Review PubMed

The role of diet and non-pharmacologic supplements in the treatment of chronic neuropathic pain: A systematic review.

Pain practice : the official journal of World Institute of Pain 2024

FINDINGS: Forty studies were included in the final review, and results were categorized according to pain type including pain related to chemotherapy-induced peripheral neuropathy (CIPN, 22 studies, including 3 prospective cohorts), diabetic peripheral neuropathy (DPN, 13 studies, including 2 prospective), complex regional pain syndrome (CRPS-I, 3 studies, including 1 prospective), and other (2 studies, both RCT). Guilongtonluofang, ninjin'yoeito, and antioxidants showed various degrees of potential effectiveness.

View Full Study on PubMed
In Vitro Study PubMed

Cyanocobalamin-Modified Colistin-Hyaluronan Conjugates: Synthesis and Bioactivity.

International journal of molecular sciences 2023

Vitamin B12 was chosen as a targeting ligand because it has its own absorption pathway in the small intestine. An in vitro release test at pH 7.4 and pH 5.2 showed an ultra-slow release of colistin of approximately 1% after 10 h.

View Full Study on PubMed
Laboratory Research PubMed

Role of Dietary Supplements in Thyroid Diseases.

Endocrine, metabolic & immune disorders drug targets 2022

CONCLUSION: After analyzing various studies on this topic, we arrived at the conclusion that although there are various claimed and observed health benefits of dietary supplements in the prevention and treatment of various thyroid disorders, still several studies have shown too many risks to be associated with the use of dietary supplements, and people using these products should be aware of these risks in order to use them very judiciously for the improvement of their thyroid status.

View Full Study on PubMed
Literature Review PubMed

Mechanistic Insights into the Link between Gut Dysbiosis and Major Depression: An Extensive Review.

Cells 2022

Recent advancements in biomedical research have demonstrated a clear correlation between gut dysbiosis (GD) or gut microbial dysbiosis and the development of anxiety or depressive behaviors. The gut microbiome communicates with the brain through the neural, immune, and metabolic pathways, either directly (via vagal nerves) or indirectly (via gut- and microbial-derived metabolites as well as gut hormones and endocrine peptides, including peptide YY, pancreatic polypeptide, neuropeptide Y, cholecystokinin, corticotropin-releasing factor, glucagon-like peptide, oxytocin, and ghrelin).

View Full Study on PubMed
Literature Review PubMed

Epigenetic Changes and Its Intervention in Age-Related Neurodegenerative Diseases.

Cellular and molecular neurobiology 2022

Epigenetic mechanisms involving the modulation of gene activity without modifying the DNA bases are reported to have lifelong effects on mature neurons in addition to their impact on synaptic plasticity and cognition. Studies have demonstrated in experimental models of neurodegenerative disorders that manipulations of these two mechanisms influence the susceptibility of neurons to degeneration and apoptosis.

View Full Study on PubMed
TEST — CODE SNIPPETS IS WORKING
Research Use Only

The following peer-reviewed publications reference compounds for laboratory and in vitro research purposes only. Not for human or animal use. Not intended to diagnose, treat, cure, or prevent any disease or condition.

PubMed — Peer-Reviewed Research

Published Scientific Research

Peer-reviewed laboratory studies investigating research peptides

Molecular Analysis PubMed

Description of TEMPI syndrome in Waldenström's macroglobulinemia.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 2025

BACKGROUND: TEMPI syndrome (telangiectasia, erythrocytosis with increased erythropoietin, monoclonal gammopathy, perinephritic fluid collections, and intrapulmonary shunts) was described by David Sykes in 2011. By the end of March 2025, we have found descriptions of 35 cases of TEMPI syndrome in the literature. Non-IgM monoclonal gammopathy of clinical significance was diagnosed in 23 patients, multiple myeloma in 10 patients and Waldenström's macroglobulinemia in only 2 cases. Sykes estimated

View Full Study on PubMed →
Systematic Review PubMed

The role of diet and non-pharmacologic supplements in the treatment of chronic neuropathic pain: A systematic review.

Pain practice : the official journal of World Institute of Pain 2024

FINDINGS: Forty studies were included in the final review, and results were categorized according to pain type including pain related to chemotherapy-induced peripheral neuropathy (CIPN, 22 studies, including 3 prospective cohorts), diabetic peripheral neuropathy (DPN, 13 studies, including 2 prospective), complex regional pain syndrome (CRPS-I, 3 studies, including 1 prospective), and other (2 studies, both RCT). Guilongtonluofang, ninjin'yoeito, and antioxidants showed various degrees of potential effectiveness.

View Full Study on PubMed →
In Vitro Study PubMed

Cyanocobalamin-Modified Colistin-Hyaluronan Conjugates: Synthesis and Bioactivity.

International journal of molecular sciences 2023

Vitamin B12 was chosen as a targeting ligand because it has its own absorption pathway in the small intestine. An in vitro release test at pH 7.4 and pH 5.2 showed an ultra-slow release of colistin of approximately 1% after 10 h.

View Full Study on PubMed →
Structural Analysis PubMed

Role of Dietary Supplements in Thyroid Diseases.

Endocrine, metabolic & immune disorders drug targets 2022

CONCLUSION: After analyzing various studies on this topic, we arrived at the conclusion that although there are various claimed and observed health benefits of dietary supplements in the prevention and treatment of various thyroid disorders, still several studies have shown too many risks to be associated with the use of dietary supplements, and people using these products should be aware of these risks in order to use them very judiciously for the improvement of their thyroid status.

View Full Study on PubMed →
Literature Review PubMed

Mechanistic Insights into the Link between Gut Dysbiosis and Major Depression: An Extensive Review.

Cells 2022

Recent advancements in biomedical research have demonstrated a clear correlation between gut dysbiosis (GD) or gut microbial dysbiosis and the development of anxiety or depressive behaviors. The gut microbiome communicates with the brain through the neural, immune, and metabolic pathways, either directly (via vagal nerves) or indirectly (via gut- and microbial-derived metabolites as well as gut hormones and endocrine peptides, including peptide YY, pancreatic polypeptide, neuropeptide Y, cholecystokinin, corticotropin-releasing factor, glucagon-like peptide, oxytocin, and ghrelin).

View Full Study on PubMed →
Literature Review PubMed

Epigenetic Changes and Its Intervention in Age-Related Neurodegenerative Diseases.

Cellular and molecular neurobiology 2022

Epigenetic mechanisms involving the modulation of gene activity without modifying the DNA bases are reported to have lifelong effects on mature neurons in addition to their impact on synaptic plasticity and cognition. Studies have demonstrated in experimental models of neurodegenerative disorders that manipulations of these two mechanisms influence the susceptibility of neurons to degeneration and apoptosis.

View Full Study on PubMed →

Important Research Notice: These products are research chemicals intended exclusively for in vitro laboratory research by qualified professionals. Not for human or animal consumption. Not approved by the FDA for any therapeutic purpose. Sold strictly for scientific research applications only.

Frequently Asked Questions

Essential information about our research-grade peptides and quality standards.

Peptides are short chains of amino acids linked by peptide bonds, typically consisting of 2-50 amino acids. They serve as the building blocks of proteins and play crucial roles in biological processes.

Research peptides are synthesized versions of naturally occurring peptides, manufactured to precise specifications for use in scientific studies.

Key characteristics: High purity (≥98%), lyophilized form for stability, accompanied by Certificates of Analysis (COA), and manufactured under strict quality control protocols.

Peptide purity refers to the percentage of the target peptide present in a sample, measured via High-Performance Liquid Chromatography (HPLC).

Our Standard: All our research peptides maintain ≥98% purity, verified by third-party laboratory testing and documented in our Certificates of Analysis.

Higher purity is critical for research because impurities can interfere with experimental results and compromise the reproducibility of studies.

All products are supplied in lyophilized powder form within sterile, sealed vials. This format provides:

  • Maximum stability: Extended shelf life compared to liquid solutions
  • Precise measurement: Researchers can work with desired quantities
  • Contamination protection: Sealed vials prevent environmental exposure
  • Shipping durability: Powder form is more stable during transit

Lyophilized peptides:

  • Store at -4°F for long-term storage (up to 24 months)
  • Store at 36-46°F (refrigerated) for short-term storage (up to 3 months)
  • Keep away from light, moisture, and repeated temperature fluctuations

We supply research-grade peptides to:

  • Academic and university research laboratories
  • Pharmaceutical and biotechnology companies
  • Independent research institutions
  • Licensed professionals conducting legitimate scientific research

We maintain rigorous quality control through a multi-step verification process:

  • HPLC Analysis: Every batch tested to verify ≥98% purity
  • Mass Spectrometry: Molecular weight confirmation for peptide identity
  • Third-Party Testing: Independent laboratory verification
  • Sterility Protocols: Aseptic handling and packaging procedures
  • Batch Documentation: Complete traceability from synthesis to delivery

"Research Use Only" (RUO) is a classification indicating that a product is intended exclusively for laboratory research and experimental investigation.

All orders are shipped with research-grade handling protocols:

  • Packaging: Insulated containers with cold packs when required
  • Carriers: USPS Priority Mail
  • Processing: Orders placed before 12 PM EST ship same business day
  • Tracking: Full tracking information provided via email

We stand behind every product:

  • Quality guarantee: Full replacement or refund if products don't meet stated specifications
  • Shipping issues: Free replacement for damaged or lost shipments
  • Unopened returns: Accepted within 30 days for store credit
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⚠️ Research Use Only — Legal Acknowledgment

All products on this website are sold strictly for in vitro research and laboratory use only.

  • Not for human or veterinary use, consumption, or application
  • Not FDA-approved to diagnose, treat, cure, or prevent any disease
  • Buyer assumes full responsibility for legal compliance in their jurisdiction

By clicking "Accept," you confirm:

  • You are at least 21 years of age
  • You are a qualified researcher or laboratory professional
  • You represent the affiliation type selected above
  • You understand these products are for research purposes only