⚠️FOR RESEARCH PURPOSES ONLY
ResearchPeptide

AICAR

Published Research

PubMed-indexed studies for AICAR

Research

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity.

Nature 2009
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Research

AICAR, an AMPK activator, protects against cisplatin-induced acute kidney injury through the JAK/STAT/SOCS pathway.

Biochemical and biophysical research communications 2019
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Research

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.

Cell death & disease 2021
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Research

FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination.

Autophagy 2022
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Research

AMPK activator AICAR in combination with anti-mouse IL10 mAb restores the functionality of intra-tumoral Tfh cells in the 4T1 mouse model.

Cellular immunology 2022
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Research

Prior treatment with the AMPK activator AICAR induces subsequently enhanced glucose uptake in isolated skeletal muscles from 24-month-old rats.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2018
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⚠️ For laboratory research only. Not for human use.